EpiVax: 14 To Watch in Rhode Island in 2014
Thursday, January 02, 2014
"EpiVax is a privately held immuno-informatics company with a truly global presence. We not only successfully provide services to large and small biotech companies, we also design our own T cell vaccines and are developing a first-in-class therapy called Tregitopes," they write.
As for Tregitopes, they were discovered in 2008 by the team of Dr. Annie De Groot and William Martin at EpiVax, and the program is currently managed by Scientific Director Leslie Cousens, Ph.D. The original discovery was published in the journal Blood in 2008. Tregitopes are linear sequences contained within the framework of monoclonal antibodies and immunoglobulin G (also known as gamma globulin). The Tregitopes act as a natural "off switch” and have been shown in standard preclinical models as well as by collaborating laboratories to suppress and treat autoimmune disease, allergy, and to effectively suppress the imunogenicity of co-administered proteins.
While it might sound somewhat complicated to the average person, what you should know is that EpiVax is at the forefront of scientific discoveries in vaccines and immunology, right here in Rhode Island. Stay tuned for major developments to come from EpiVax.
Related Slideshow: 14 To Watch in RI in 2014
One of the most exciting GoLocal up-and-comers to watch is only just starting to make her mark, as SlowFoodURI founder Neill is a URI senior in Kingston.
Named a Truman Scholar last spring—one of only 61 nationwide—Neill founded Slow Food URI "with a passion for food and great concern for the wellbeing of all things."
Co-owner of Midday Records and guitarist for Satellites Fall, Moore is making a major impact on the New England music scene. While he's been part of the Midday label since 2008, Moore has been taking it to another level, putting out a series compilation albums featuring some of the best bands in the area titled New England Indie Alt Rock, as well as a digital compilation with 80 bands titled Onefundboston.org: A Benefit For The Boston Marathon".
Brierley is a rising fashion designer who studied at the Rhode Island School of Design, as well as the Fashion Institute of Technology in New York, and resisted the lure of the Big Apple to open her flagship store in Newport.
"I just wanted to do something fresh," Brierley told GoLocal in July. "I love how much the community in Newport appreciates what we do and our windows. It is a rewarding connection to a community."
12 to Watch in 2012...Best Brunch in Providence in 2013...multiple nods for the James Beard Award...Farmstead's Matt Jennings is not one to rest on his laurels atop the always competitive Providence and RI culinary scenes.
With a loyal Twitter base nearing 10,000 followers, Jennings—known as "Providence's Pied Piper of Cheese" and "Prince of Pork"—continues to advance the culture and excellence that landed Providence atop Travel + Leisure's list for Food/Drink/Restaurants—the #1 city in the country—in 2012.
Providence-based biotech EpiVax, Inc., is an immunology company that has "developed comprehensive analytical capabilities in the field of computational immunology" and applies those tools to re-engineer therapeutic proteins and to design new vaccines. The company continues to forge ahead as a groundbreaking health science company in the state. Basically, as stated on their website, they "do it all."
Microfinance proponent and co-founder of the Capital Good Fund, Posner is working to be the "best best financial empowerment organization in America by providing high-quality, innovative and transformational financial services to underserved families."
In October, the National Consumer Law Center gave Rhode Island a "C" for debt protection laws for consumers in the state. Posner told GoLocal that "One of the biggest problems is that we are the only New England state that allows payday lenders to charge more than 36% APR. In fact, in RI they can charge up to 260% APR thanks to a special carve out in the general laws. These loans target the poor and trap them in a cycle of debt that leads to tremendous stress and a significant drain on their finances."
This Betaspring darling and Walker Williams brainchild is set to revolutionize the way that custom-designed tee-shirts are produced. The company allows customers to design a style, set a sales goal, and pre-order the product, cutting out the need for a middle man.
"No paying thousands of dollars upfront, no guessing how many shirts or what sizes you'll need, and no passing out t-shirts one by one and chasing people down for cash," writes Teespring on their website. And folks are taking note—Forbes contributor Alexander Taub wrote in January of Teepsring, "Is this Rhode Based startup the future of custom apparel?"
This consummate public relations professional struck out on her own in 2013 after years at RDW Group with Patti Doyle Communications, and shows no sign of slowing down.
Doyle's clients include Twin River Casino, which officially launched its table game offerings after a successful 2012 referendum. The gaming licensing process has been slow and deliberate in Massachusetts, which in 2011 approved legislation to allow up to 3 casinos and a slots parlor, promising stiff competition to Twin River once those are up and operational. Once the fight is on, watch for Doyle to be spearheading the communications strategy from Rhode Island's third-largest source of revenue.
A 2013 RI YWCA "Woman of Achievement," Cano-Morales is no stranger to accolades for her work in the community. The Central Falls native is the Director of the Latino Policy Institute at Roger Williams University and is Chair of the Central Falls School District Board of Trustees.
Cano-Morales was no stranger to GoLocal's Hot or Not lists this year, earning multiple "hot" nods for her work, including LPI reports focusing on the state's latino workforce. And Cano-Morales is forward thinking when it comes to educational opportunities, and talked with GoLocal about the biggest challenges she saw facing Rhode Island.
Which way will the wind blow in 2014 for the Deepwater Wind project?
2013 saw Deepwater Wind win key leases in the first round of federal auctions in August for offshore wind projects, taking the bids at just over $3.8 million. In December, the state properties committee approved agreements to allow for an underwater transmission cable to go through Scarborough State Beach, to allow Deepwater to build a "demonstration" wind farm off of Block Island.
In 2012, the legalization of same-sex marriage was the top social and legal issue addressed and approved by the General Assembly. Will the full-scale legalization of marijuana be on the table in 2014? Expect to see State Rep. Edith Ajello front and center in the debate if so.
While medical marijuana and the decriminalization of the possession of small amounts of it have moved through the General Assembly, the question is whether Rhode Island will follow Colorado and Washington's lead and pass full-scale legalization legislation.
Will he, or won't he?
One of the burning questions for 2014 is whether the former two-time Mayor of Providence will toss his hat in the ring for a third go at the office.
GoLocal posed the questions back in September, asking political experts and pundits their thoughts on the matter. Of the longest-serving Mayor of Providence, who was in office from 1975 to 1984 and again from 1991 to 2002, Darrell West of the Brookings Institute and formerly of Brown's Taubman Center for Public Policy said, "There would be tremendous media and public interest if Cianci ran. It would turn this into a high-profile campaign. It is not clear what will be the deciding factor. It would be very different if Cianci is in the race or not."
In October, GoLocal broke that Clay Pell, grandson of six-term Rhode Island Senator Claiborne Pell, was weighing a potential 2014 gubernatorial run in Rhode Island.
Pell, who's resume includes being a White House staffer and Coast Guard Reserve Officer, married Olympic figure skater Michelle Kwan in a ceremony at First Unitarian Church in Providence in 2013, and was appointed by President Obama as Deputy Assistant Secretary for International and Foreign Language Education in April.
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